Mark papa guardado biography

Abstract

Crimean-Congo hemorrhagic fever (CCHF) is a tickborne infection that can range from asymptomatic to fatal and has been described in >30 countries. Early identification and isolation of patients with suspected or confirmed CCHF and the use of appropriate prevention and control measures are essential for preventing human-to-human transmission. Here, we provide an overview of the epidemiology, clinical features, and prevention and control of CCHF. CCHF poses a continued public health threat given its wide geographic distribution, potential to spread to new regions, propensity for genetic variability, and potential for severe and fatal illness, in addition to the limited medical countermeasures for prophylaxis and treatment. A high index of suspicion, comprehensive travel and epidemiologic history, and clinical evaluation are essential for prompt diagnosis. Infection control measures can be effective in reducing the risk for transmission but require correct and consistent application.

Keywords: Crimean-Congo hemorrhagic fever, viruses, vector-borne infections, bunyavi

Hells Angels MC criminal allegations and incidents in California

Main article: Hells Angels MC criminal allegations and incidents

Numerous police and international intelligence agencies classify the Hells Angels Motorcycle Club as a motorcycle gang and contend that members carry out widespread violent crimes, including drug dealing, trafficking in stolen goods, gunrunning, extortion, and prostitution rings.[1][2] Members of the organization have continuously asserted that they are only a group of motorcycle enthusiasts who have joined to ride motorcycles together, to organize social events such as group road trips, fundraisers, parties, and motorcycle rallies, and that any crimes are the responsibility of the individuals who carried them out and not the club as a whole.[3][4]

There are more Hells Angels chapters in California than in any other U.S. state.[5] With over 300 members statewide, the Hells Angels are the most significant motorcycle gang in California in terms of membership and criminal activity. The club has a

Abstract

Crimean-Congo hemorrhagic fever (CCHF), caused by CCHF virus, is a tickborne disease that can cause a range of illness outcomes, from asymptomatic infection to fatal viral hemorrhagic fever; the disease has been described in >30 countries. We conducted a literature review to provide an overview of the virology, pathogenesis, and pathology of CCHF for clinicians. The virus life cycle and molecular interactions are complex and not fully described. Although pathogenesis and immunobiology are not yet fully understood, it is clear that multiple processes contribute to viral entry, replication, and pathological damage. Limited autopsy reports describe multiorgan involvement with extravasation and hemorrhages. Advanced understanding of CCHF virus pathogenesis and immunology will improve patient care and accelerate the development of medical countermeasures for CCHF.

Keywords: Crimean-Congo hemorrhagic fever, viruses, vector-borne infections, bunyavirus, viral hemorrhagic fever, countermeasure, vaccine, treatment


Crimean-Congo hemorrhagic fever (CCHF) was clinically cat

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